David Marshall
Licensed Real Estate Salesperson
REALTOR®
Glens Falls, NY

105 N Main Street, Syracuse, NY 13212

New
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Property Description

Well-maintained, single-story commercial building at 105 N Main Street in North Syracuse, NY. This 2,244 square foot medical office has been in continuous professional use for over 60 years and currently houses an established optometry practice operating at this location for 29 years. The building sits on a 0.23-acre lot with 15 dedicated parking spaces and offers high visibility on North Main Street. The property received a new roof in 2024, significantly reducing near-term capital expenditure risk for the buyer. The interior features a professionally designed layout with reception and optical retail areas, multiple fully equipped exam rooms, private offices, and a laboratory space. The floor plan is well-suited for optometry, ophthalmology, dental, dermatology, chiropractic, physical therapy, counseling, or general professional office use. Key property details: 2,244 SF on a single level. Built in 1950, well-maintained with a modern interior buildout. New roof installed in 2024. 15 on-site parking spaces (approximately 7 per 1,000 SF). Zoned for medical and professional office use. Single-tenant, owner-occupied. This property is located in the heart of North Syracuse, within the rapidly growing Central New York economic corridor. The area is positioned to benefit significantly from the Micron Technology semiconductor fabrication facility currently under construction in nearby Clay, NY, which is expected to bring substantial job growth and commercial demand to the surrounding communities. The building is available on its own at $400,000 or as part of a package with the established optometry practice (offered separately at $550,000). Seller financing may be available for qualified buyers.

105 N Main Street | MLS# S1683136

This commercial property located at 105 N Main Street, Syracuse, NY 13212 is currently listed for sale with an asking price of $400,000. N Main Street is located within the North Syracuse school district. Search Syracuse real estate on david-marshall.coldwellbankerprime.com today.

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Property Features

Property Type: Commercial - Office
Cooling: Central Air
Heating: Electric, Gas, Forced Air
Lot Size: 0.23 Acres
Roof Type: Asphalt
Stories: 1.0
Taxes: $10,374
Year Built: 1950

Feature Descriptions

Building Features: Office, Phone System
Days on Site: 2
Exterior: Wood Siding
Lot: Rectangular, Rectangular Lot
Lot Dimensions: 49X206
Parcel#: 312401-003-000-0002-012-000-0000
Security: Intercom
Sewer: Public Sewer
Utilities: Sewer Connected

Local Schools

School District: North Syracuse

Demographics

Listed By / Shown By

Listing By

Agency Name: Home With Us Realty Group, LLC
Agency Phone: 315-677-7062

Shown By

Agent Name: David Marshall
Agent Phone: (518) 222-7924 Cell
Agency Title: Coldwell Banker Prime Properties

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Disclaimer: All information deemed reliable but not guaranteed. All properties are subject to prior sale, change or withdrawal. Neither listing broker(s) or information provider(s) shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless. Listing(s) information is provided for consumers personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information on this site was last updated 05/21/2026. The listing information on this page last changed on 05/21/2026. The data relating to real estate for sale on this website comes in part from the Internet Data Exchange program of Delta Media Group MLS (last updated Thu 05/21/2026 2:26:01 PM EST) or Global MLS (last updated Thu 05/21/2026 2:23:25 PM EST) or New York State Alliance MLS (last updated Thu 05/21/2026 2:23:30 PM EST) or Hudson Valley Catskill Region MLS (last updated Thu 05/21/2026 2:21:43 PM EST) or OneKey MLS (last updated Thu 05/21/2026 2:19:51 PM EST). Real estate listings held by brokerage firms other than Coldwell Banker Prime Properties may be marked with the Internet Data Exchange logo and detailed information about those properties will include the name of the listing broker(s) when required by the MLS. All rights reserved.

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